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Biomaterials Bone Grafting and Tissue Engineering: The Cutting-Edge Guide to Regenerative Bone Repair

Roger Turner

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Published in Preprosthetic And Maxillofacial Surgery: Biomaterials Bone Grafting And Tissue Engineering (Woodhead Publishing In Biomaterials)

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: The Need for Advanced Bone Repair Solutions

Bone defects and injuries pose significant challenges in healthcare, affecting millions of patients worldwide. Traditional bone grafting techniques using autografts and allografts have limitations, including donor site morbidity, immune rejection, and limited availability. Biomaterials bone grafting and tissue engineering offer promising solutions to overcome these challenges, enabling personalized and regenerative bone repair.

Preprosthetic and Maxillofacial Surgery: Biomaterials Bone Grafting and Tissue Engineering (Woodhead Publishing in Biomaterials)

Preprosthetic and Maxillofacial Surgery: Biomaterials, Bone Grafting and Tissue Engineering (Woodhead Publishing Series in Biomaterials)

4 out of 5

Language	:	English
File size	:	10371 KB
Text-to-Speech	:	Enabled
Screen Reader	:	Supported
Enhanced typesetting	:	Enabled
Print length	:	406 pages

Chapter 1: Biomaterials for Bone Grafting: Properties and Applications

This chapter explores the fundamental properties and applications of biomaterials used in bone grafting. Readers will gain insights into the physiochemical characteristics, biocompatibility, biodegradability, and osteoinductive potential of various materials, including ceramics, metals, polymers, and composites. The chapter also covers the design and fabrication of scaffolds, providing the foundation for tissue engineering approaches.

Chapter 2: Advances in Tissue Engineering for Bone Regeneration

Chapter 2 delves into the exciting field of tissue engineering for bone regeneration. It introduces the principles of tissue engineering, including cell culture, scaffold design, and bioreactor technology. The chapter highlights cell sources, such as stem cells and progenitor cells, and their role in bone formation. Readers will learn about the latest advancements in scaffold materials, including nanocomposites and 3D-printed scaffolds, and their applications in bone repair.

Chapter 3: Bone Graft Substitutes and Their Clinical Applications

This chapter provides a comprehensive overview of commercially available bone graft substitutes and their clinical applications. Readers will explore the advantages and disadvantages of different materials, including hydroxyapatite, calcium sulfate, and collagen-based scaffolds. The chapter discusses the indications, surgical techniques, and outcomes of bone graft substitutes in various clinical scenarios, such as dental implants, spinal fusion, and fracture repair.

Chapter 4: Growth Factors and Gene Therapy in Bone Regeneration

Chapter 4 delves into the emerging field of growth factors and gene therapy for bone regeneration. Readers will discover the role of growth factors, such as bone morphogenetic proteins (BMPs) and transforming growth factor-beta (TGF-beta),in stimulating bone formation. The chapter explores the delivery methods and clinical applications of growth factors, including gene-activated matrices and stem cell-based therapies.

Chapter 5: Current Challenges and Future Perspectives

The final chapter examines the current challenges and future perspectives in biomaterials bone grafting and tissue engineering. It addresses the need for standardized testing protocols, long-term clinical studies, and regulatory approval. The chapter also highlights potential research directions, including biomimetic materials, artificial intelligence, and personalized medicine. Readers will gain insights into the promising future of bone regeneration and its implications for patient care.

: Revolutionizing Bone Repair through Biomaterials and Tissue Engineering

Biomaterials bone grafting and tissue engineering represent a paradigm shift in bone repair, offering personalized and regenerative solutions to address the growing need for effective bone regeneration. This comprehensive guide provides a thorough understanding of biomaterials, tissue engineering techniques, clinical applications, and future perspectives. By equipping healthcare professionals with the latest advancements in this field, the book empowers them to improve patient outcomes and revolutionize the treatment of bone defects and injuries.

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Preprosthetic and Maxillofacial Surgery: Biomaterials, Bone Grafting and Tissue Engineering (Woodhead Publishing Series in Biomaterials)

4 out of 5